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| Registros recuperados: 99 | |
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| Borges,F.T.; Reis,L.A.; Schor,N.. |
| Interest in the role of extracellular vesicles in various diseases including cancer has been increasing. Extracellular vesicles include microvesicles, exosomes, apoptotic bodies, and argosomes, and are classified by size, content, synthesis, and function. Currently, the best characterized are exosomes and microvesicles. Exosomes are small vesicles (40-100 nm) involved in intercellular communication regardless of the distance between them. They are found in various biological fluids such as plasma, serum, and breast milk, and are formed from multivesicular bodies through the inward budding of the endosome membrane. Microvesicles are 100-1000 nm vesicles released from the cell by the outward budding of the plasma membrane. The therapeutic potential of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Extracellular vesicles; Cell biology; Kidney diseases; Diagnosis; Treatment. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001000824 |
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| Sangiorgio,F.; Sakate,M.; Nogueira,R. M. B.; Tostes,R. A.. |
| The present work evaluated histopathological aspects in experimental envenomation of dogs with Crotalus durissus terrificus venom. Twenty-eight mixed breed adult dogs were divided into three groups of seven animals each: Group I - only venom; Group II - venom + 50ml antiophidic serum + fluid therapy; Group III - venom + 50ml antiophidic serum + fluid therapy + urine alkalization. Lyophilized venom of Crotalus durissus terrificus was reconstituted in saline solution and inoculated subcutaneously at the dose of 1mg/kg body weight. Three animals of each group were subjected to euthanasia, and their muscular tissue, brain, spleen, kidneys, heart, lungs, stomach, small and large intestines, and popliteal lymph node fragments were collected for histopathological... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Histopathology; Crotalus durissus terrificus; Dogs; Treatment; Intoxication. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992008000100007 |
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| Goulletquer, Philippe; Geairon, Philippe; Faury, Nicole; Razet, Daniel; Soletchnik, Patrick; Gras, Paul; Adessi, L.. |
| In European waters, significant economic damages to wooden structures are caused by bivalves molluscs and crustaceans. Treatments like copper-chrome-arsenic mixtures (CCA) were designed to prevent settlement of these wood borer species. However, limited and conflicting evidence regarding the toxicity to non-target organisms are available in the literature. This report aims to provide insights regarding the CCA leachates' toxicity to an important aquaculture species, the blue mussel Mytilus edulis for which much information on normal and stressed physiology is available for purposes of comparisons. The mussels are usually considered as a particularly suitable species for biological monitoring (Smaal and Widdows, 1994). To address the CCA leachate issue, two... |
| Tipo: Text |
Palavras-chave: Bivalvia; Mussel; Mytilus edulis; Copper-chrome-arsenic (CCA); Treatment; Feeding; Absorption. |
| Ano: 1996 |
URL: http://archimer.ifremer.fr/doc/00043/15437/12788.pdf |
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| Ono,Ekaterina A. Durymanova; Iamamoto,Keila; Castilho,Juliana G.; Carnieli Jr.,Pedro; Oliveira,Rafael de Novaes; Achkar,Samira M.; Carrieri,Maria L.; Kotait,Ivanete; Brandão,Paulo E.. |
| Rabies is a zoonotic disease that affects all mammals and leads to more than 55,000 human deaths every year, caused by rabies virus (RABV) (Mononegavirales: Rhabdoviridae: Lyssavirus). Currently, human rabies treatment is based on the Milwaukee Protocol which consists on the induction of coma and massive antiviral therapy. The aim of this study was to assess the decrease in the titer of rabies virus both in vitro and in vivo using short-interfering RNAs. To this end, three siRNAs were used with antisense strands complementary to rabies virus nucleoprotein (N) mRNA. BHK-21 cells monolayers were infected with 1000 to 0.1 TCID50 of PV and after 2 hours the cells were transfected with each of tree RNAs in separate using Lipofectamine-2000. All three siRNAs... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rabies; RNA interference; SiRNAs; Antiviral; Treatment. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000300034 |
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| Vervloet,Letícia Alves; Marguet,Christophe; Camargos,Paulo Augusto Moreira. |
| This manuscript reviewed the literature on infection by Mycoplasma pneumoniae with emphasis on etiological aspects of childhood community-acquired pneumonias. Bibliographical research was carried out from Pubmed Medline, MDConsult, HighWire, LILACS, and direct research over the past 10 years with the following keywords: Mycoplasma pneumoniae, pneumonia, and childhood. Fifty-four articles were selected. Mycoplasma pneumoniae has a high incidence in childhood. Clinical presentation includes respiratory and extrarespiratory symptoms. Mycoplasma pneumoniae lung infection can be confused with viral or bacterial pneumonia and is unresponsive to beta-lactams. In addition, co-infections have been reported. Mycoplasma pneumoniae infection occurs in all age groups,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mycoplasma pneumoniae; Pneumonia; Extrapulmonary findings; Diagnosis; Treatment. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000500012 |
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| JORGE,M. T.; RIBEIRO,L. A.. |
| Envenomation caused by snakes of the Bothrops genus produces a lesion in the bite site and can result in extensive necrosis. The dead tissue can be secondarily infected by bacteria that come from the snake, and the bacteria can be inoculated at the moment of the bite. The bacteria that most commonly cause infection are the enterobacteria, mainly Morganella morganii, Proteus rettgeri, Enterobacter sp., and Escherichia coli. Group D streptococci including here Enterococcus sp. and the Bacteroides sp. are also involved. Based on a study of the sensibility of these bacteria, it has been suggested that this infection must be treated with chloramphenicol, as a sole antimicrobial agent, or with the combinations of benzylpenicillin or ampicillin with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Snakebite; Bothrops; Infection; Antimicrobial agents; Treatment. |
| Ano: 1997 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-79301997000200002 |
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| Magalhães,Felipe Antunes; Valadares Filho,Sebastião de Campos; Menezes,Gustavo Chamon de Castro; Gionbelli,Mateus Pies; Zanetti,Diego; Machado,Marcelo Grossi; Pina,Douglas dos Santos; Komura,Koiti. |
| The objective of this study was to evaluate low and high Brix diets, treated or not with 5 g of calcium oxide per kg of natural matter, and corn silage on intake, digestibility and performance of beef cattle. Forty cattle with initial body weight (BW) of 350 kg were used: five composed the control group, 30 were distributed into random blocks (control) and the other five were distributed in a 5 × 5 incomplete Latin square, with the objective of determining digestibility. The 30 animals evaluated for performance were slaughtered and empty body weight (EPW), carcass dressing and meat cuts were determined. The diet with corn silage (CS) presented the best intake of the other ingredients and the best weight gain, except for neutral detergent fiber intake in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Digestibility; Ethanol; Fermentation; Treatment. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982012000600026 |
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| Garcia,Rosa; Pondé,Milena; Lima,Manuela; Souza,Alba Regina de; Stolze,Silvia Maria de O.; Badaró,Roberto. |
| As a result of the potent drug combinations of reverse transcriptase inhibitors and protease inhibitors currently available, it is now possible to achieve extreme reductions in the numbers of viral particles in the peripheral blood of HIV-positive patients undergoing treatment, to the point that they are undetectable. Moreover, the immunological recovery resulting from continued and prolonged use of these drugs significantly reduces both mortality and the incidence of opportunistic infections. However, the strict therapeutic regimens required, the number of pills, adverse events and the stigma of a disease that requires the patient to introduce pill-taking into his/her lifestyle brings into question one aspect of mental health, which is motivation to do... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Motivation; Adherence; HIV-Positive/AIDS; Treatment. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000600007 |
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| Özgenç,Onur; Avcı,Meltem; Arı,Alpay; Çelebi,İsmail Yunus; Coşkuner,Seher Ayten. |
| In this paper a disseminated persistent Nocardia cyriacigeorgicainfection in an immunocompetent patient is described. The patient's long-term treatment, as well as its implications for managing similar cases in the future, is emphasized. Presenting with high fever, multiple nodules, and ulcerative cutaneous lesions of body sites, the patient was treated with various antimicrobials. Under combined therapy, empyema and arthritis, leading to disseminated nocardiosis, were seen. The overall treatment course was 28 months. It can be concluded that the choice of the antibiotics and optimal duration of treatment are uncertain; therefore the treatment of nocardiosis requires expertise. |
| Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Nocardia cyriacigeorgica; Chronic infection; Treatment. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500556 |
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| COLPO,GABRIELA D.; ASCOLI,BRUNA M.; WOLLENHAUPT-AGUIAR,BIANCA; PFAFFENSELLER,BIANCA; SILVA,EMILY G.; CIRNE-LIMA,ELIZABETH O.; QUEVEDO,JOÃO; KAPCZINSKI,FLÁVIO; ROSA,ADRIANE R.. |
| Mesenchymal stem cells (MSCs) are multipotent progenitor cells that have the capacity to differentiate into all lineages of mesodermal origin, e.g., cartilage, bone, and adipocytes. MSCs have been identified at different stages of development, including adulthood, and in different tissues, such as bone marrow, adipose tissue and umbilical cord. Recent studies have shown that MSCs have the ability to migrate to injured sites. In this regard, an important characteristic of MSCs is their immunomodulatory and anti-inflammatory effects. For instance, there is evidence that MSCs can regulate the immune system by inhibiting proliferation of T and B cells. Clinical interest in the use of MSCs has increased considerably over the past few years, especially because... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mesenchymal stem cells; Treatment; Neurodegenerative disease; Psychiatric disorders. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000301435 |
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| Ribeiro,L.; Busnello,J.V.; Kauer-Sant'Anna,M.; Madruga,M.; Quevedo,J.; Busnello,E.A.D.; Kapczinski,F.. |
| Mirtazapine is an antidepressant whose side effect profile differs from that of first-line agents (selective serotonin reuptake inhibitors) used in the treatment of panic disorder. The present study compared the effect of mirtazapine and fluoxetine in the treatment of panic disorder in a double-blind, randomized, flexible-dose trial conducted with outpatients. After a 1-week single-blind placebo run-in, 27 patients entered an 8-week double-blind phase in which they were randomly assigned to treatment with either mirtazapine or fluoxetine. Both groups improved significantly in all but one efficacy measure (P<=0.01). ANOVA showed no significant differences between the two treatment groups in number of panic attacks, Hamilton Anxiety Scale or Sheehan... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Mirtazapine; Fluoxetine; Panic disorder; Treatment; Randomized trial. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001001000010 |
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| Pribylova,Radka; Kralik,Petr; Donnelly,Neysan; Matiasovic,Jan; Pavlik,Ivo. |
| The aim of this work was to study the expression of selected Mycobacterium avium subsp. paratuberculosis (MAP) genes connected with MAP virulence, adhesion and stress response. The temperature of 6°C and 65°C were chosen with regard to the food industry, storage conditions (refrigerator) and low-temperature pasteurization. A pH of 2.0, using lactic acid, was selected to mimic the natural environment of the stomach. Expression of selected genes was studied using real time reverse transcription PCR on three different MAP isolates. MAP isolates were chosen according to the number of their preceding cultivations. While isolates 8672 and 8819 were previously cultivated only once, MAP isolate 12146 went through four passages. Different expression profiles were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: MAP; Johne's disease; Stress; Treatment; Real time PCR. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000200049 |
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| Kunz,Airton; Steinmetz,Ricardo; Damasceno,Simone; Coldebela,Arlei. |
| Effluents from swine raising can be harmful to the environment if not correctly managed. Nitrogen (N) is usually the main element present at high concentrations in the effluent. Since the use as biofertilizer is not always a feasible alternative, the treatment of swine wastewater is necessary. Variations in N species and water solubility make the treatment difficult and expensive. Additional N removal at low cost via denitrification may be possible by recirculating nitrified effluent in the barns. In this study, raw manure (RM) was homogenized with treated effluent (TE) at RM/(RM + TE) ratios of 1.0, 0.9, 0.8, 0.7, 0.6, 0.5 and 0 in order to simulate the effect of reused water on swine wastewater nitrogen removal. Samples were collected daily during four... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Nutrient removal; Swine effluent; Treatment; Water reuse. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162012000600002 |
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| Registros recuperados: 99 | |
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